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TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development.

机译:TBVAC2020:从发现到临床开发的结核病疫苗不断发展。

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摘要

TBVAC2020 is a research project supported by the Horizon 2020 program of the European Commission (EC). It aims at the discovery and development of novel tuberculosis (TB) vaccines from preclinical research projects to early clinical assessment. The project builds on previous collaborations from 1998 onwards funded through the EC framework programs FP5, FP6, and FP7. It has succeeded in attracting new partners from outstanding laboratories from all over the world, now totaling 40 institutions. Next to the development of novel vaccines, TB biomarker development is also considered an important asset to facilitate rational vaccine selection and development. In addition, TBVAC2020 offers portfolio management that provides selection criteria for entry, gating, and priority settings of novel vaccines at an early developmental stage. The TBVAC2020 consortium coordinated by TBVI facilitates collaboration and early data sharing between partners with the common aim of working toward the development of an effective TB vaccine. Close links with funders and other consortia with shared interests further contribute to this goal.
机译:TBVAC2020是一项受欧洲委员会(EC)的Horizo​​n 2020计划支持的研究项目。它的目的是从临床前研究项目到早期临床评估的新型结核病(TB)疫苗的发现和开发。该项目建立在1998年以来由EC框架计划FP5,FP6和FP7资助的以前的合作的基础上。它成功地吸引了来自世界各地杰出实验室的新合作伙伴,目前共有40家机构。除了开发新型疫苗,结核病生物标志物的开发也被认为是促进合理疫苗选择和开发的重要资产。此外,TBVAC2020还提供了产品组合管理,可为开发初期的新型疫苗的进入,门控和优先设置提供选择标准。由TBVI协调的TBVAC2020联盟促进了合作伙伴之间的协作和早期数据共享,其共同目标是致力于开发有效的TB疫苗。与资助者和其他拥有共同利益的财团的紧密联系进一步促进了这一目标。

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